Changes in version 1.1.3 - Added the Shiny app to help users visualize the effect of each parameter and adjust the simulation options. - Added the speed.up parameter to enable experimental speed optimization. - Bug fixes and improvements. Changes in version 1.1.0 Prepare for the Bioconductor release - Fix build errors Changes in version 0.99.8 Prepare for the Bioconductor release - Tidy up the code, add more comments Changes in version 0.99.7 Prepare for the Bioconductor release - Fix build errors