Bioconductor 3.22 Released

drugfindR

This is the development version of drugfindR; to use it, please install the devel version of Bioconductor.

Investigate iLINCS for candidate repurposable drugs


Bioconductor version: Development (3.23)

This package provides a convenient way to access the LINCS Signatures available in the iLINCS database. These signatures include Consensus Gene Knockdown Signatures, Gene Overexpression signatures and Chemical Perturbagen Signatures. It also provides a way to enter your own transcriptomic signatures and identify concordant and discordant signatures in the LINCS database.

Author: Ali Sajid Imami [aut, cre] ORCID iD ORCID: 0000-0003-3684-3539 , Smita Sahay [aut] ORCID iD ORCID: 0009-0003-4377-8963 , Justin Fortune Creeden [aut] ORCID iD ORCID: 0000-0003-3123-8401 , Robert Erne McCullumsmith [ctb, fnd] ORCID iD ORCID: 0000-0001-6921-7150

Maintainer: Ali Sajid Imami <Ali.Sajid.Imami at gmail.com>

Citation (from within R, enter citation("drugfindR")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("drugfindR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("drugfindR")
drugfindR HTML R Script
Reference Manual PDF

Details

biocViews DifferentialExpression, FunctionalPrediction, GeneSetEnrichment, Network, SingleCell, Software
Version 0.99.1349
In Bioconductor since BioC 3.23 (R-4.6)
License GPL-3 + file LICENSE
Depends R (>= 4.5.0)
Imports tibble, rlang, dplyr, purrr, readr, stringr, stats, lifecycle, S4Vectors, httr2, curl, DFplyr
System Requirements
URL https://github.com/CogDisResLab/drugfindR https://cogdisreslab.github.io/drugfindR/
Bug Reports https://github.com/CogDisResLab/drugfindR/issues
See More
Suggests AnnotationDbi, BiocStyle, biocthis, codemetar, devtools, here, httptest2, jsonlite, knitr, rmarkdown, testthat (>= 3.0.0), tidyverse, usethis
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package drugfindR_0.99.1349.tar.gz
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64) drugfindR_0.99.1349.tgz
Source Repository git clone https://git.bioconductor.org/packages/drugfindR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/drugfindR
Bioc Package Browser https://code.bioconductor.org/browse/drugfindR/
Package Short Url https://bioconductor.org/packages/drugfindR/
Package Downloads Report Download Stats