Bioconductor 3.22 Released

MutSeqR

This is the development version of MutSeqR; to use it, please install the devel version of Bioconductor.

Analysis of Error-Corrected Sequencing Data for Mutation Detection


Bioconductor version: Development (3.23)

Standard methods for analysis of mutation data following error- corrected sequencing (ECS) for the purpose of mutagencity assessment. Functions include importing the mutation lists provided by a variant caller, and a set of analytical tools for statistical testing and visualization of mutation data; comparison to COSMIC and/or germline signatures; etc.

Author: Annette E. Dodge [aut] ORCID iD ORCID: 0000-0002-0446-9055 , Andrew Williams [aut] ORCID iD ORCID: 0000-0002-7637-7686 , Danielle P.M. LeBlanc [aut] ORCID iD ORCID: 0000-0002-3847-8371 , David M. Schuster [aut] ORCID iD ORCID: 0009-0001-6316-4358 , Elena Esina [aut] ORCID iD ORCID: 0009-0002-3443-378X , Clint C. Valentine [aut] ORCID iD ORCID: 0000-0001-5630-7368 , Jesse J. Salk [aut] ORCID iD ORCID: 0000-0002-7804-0550 , Alexander Y. Maslov [aut], Christopher Bradley [aut], Carole L. Yauk [aut] ORCID iD ORCID: 0000-0002-6725-3454 , Francesco Marchetti [aut] ORCID iD ORCID: 0000-0002-9435-4867 , Matthew J. Meier [aut, cre] ORCID iD ORCID: 0000-0001-8199-8754 , Geronimo Matteo [ctb] ORCID iD ORCID: 0000-0003-0819-4471 , Health Canada's Genomics Research and Development Initiative [fnd], Canada Research Chairs Program [fnd] (CRC-2020-00060), Burroughs Wellcome Fund [fnd]

Maintainer: Matthew J. Meier <matthew.meier at hc-sc.gc.ca>

Citation (from within R, enter citation("MutSeqR")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("MutSeqR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MutSeqR")
MutSeqR: Error-Corrected Sequencing (ECS) Analysis For Mutagenicity Assessment HTML R Script
Reference Manual PDF

Details

biocViews DriverMutation, GeneTarget, GenomicVariation, Sequencing, Software, SomaticMutation, StatisticalMethod, Visualization
Version 0.99.8
In Bioconductor since BioC 3.23 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports BiocGenerics, Biostrings, BSgenome, data.table, dplyr, GenomicRanges, ggplot2, here, IRanges, ggdendro, magrittr, methods, plyranges, rlang, S4Vectors, Seqinfo, stringr, SummarizedExperiment, tidyr, VariantAnnotation
System Requirements
URL https://ehsrb-bsrse-bioinformatics.github.io/MutSeqR/
Bug Reports https://github.com/EHSRB-BSRSE-Bioinformatics/MutSeqR/issues
See More
Suggests binom, BiocManager, BiocStyle, bs4Dash, BSgenome.Hsapiens.UCSC.hg38, BSgenome.Mmusculus.UCSC.mm10, car, colorspace, dendsort, doBy, DT, ExperimentHub, fmsb, fs, ggrepel, gtools, htmltools, httr, knitr, lme4, magick, MutSeqRData, openxlsx, packcircles, patchwork, RColorBrewer, reticulate, rmarkdown, scales, shiny, testthat (>= 3.0.0), trackViewer, withr, yaml, xml2
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MutSeqR_0.99.8.tar.gz
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/MutSeqR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/MutSeqR
Bioc Package Browser https://code.bioconductor.org/browse/MutSeqR/
Package Short Url https://bioconductor.org/packages/MutSeqR/
Package Downloads Report Download Stats