BiFET

This is the development version of BiFET; for the stable release version, see BiFET.

Bias-free Footprint Enrichment Test


Bioconductor version: Development (3.21)

BiFET identifies TFs whose footprints are over-represented in target regions compared to background regions after correcting for the bias arising from the imbalance in read counts and GC contents between the target and background regions. For a given TF k, BiFET tests the null hypothesis that the target regions have the same probability of having footprints for the TF k as the background regions while correcting for the read count and GC content bias. For this, we use the number of target regions with footprints for TF k, t_k as a test statistic and calculate the p-value as the probability of observing t_k or more target regions with footprints under the null hypothesis.

Author: Ahrim Youn [aut, cre], Eladio Marquez [aut], Nathan Lawlor [aut], Michael Stitzel [aut], Duygu Ucar [aut]

Maintainer: Ahrim Youn <Ahrim.Youn at jax.org>

Citation (from within R, enter citation("BiFET")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("BiFET")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BiFET")
A Guide to using BiFET HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews ATACSeq, DNaseSeq, Epigenetics, GeneRegulation, Genetics, ImmunoOncology, RIPSeq, Software, Transcription
Version 1.27.0
In Bioconductor since BioC 3.7 (R-3.5) (6.5 years)
License GPL-3
Depends R (>= 3.5.0)
Imports stats, poibin, GenomicRanges
System Requirements
URL
See More
Suggests rmarkdown, testthat, knitr
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package BiFET_1.27.0.tar.gz
Windows Binary (x86_64) BiFET_1.27.0.zip (64-bit only)
macOS Binary (x86_64) BiFET_1.27.0.tgz
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/BiFET
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/BiFET
Bioc Package Browser https://code.bioconductor.org/browse/BiFET/
Package Short Url https://bioconductor.org/packages/BiFET/
Package Downloads Report Download Stats