%\VignetteIndexEntry{GGtools Bioinfo Application note support } %\VignetteDepends{} %\VignetteKeywords{Genetical genomics,SNP,expression} %\VignettePackage{GGtools} % % NOTE -- ONLY EDIT THE .Rnw FILE!!! The .tex file is % likely to be overwritten. % \documentclass[12pt]{article} \usepackage{amsmath,pstricks} % With MikTeX 2.9, using pstricks also requires using auto-pst-pdf or running % pdflatex will fail. Note that using auto-pst-pdf requires to set environment % variable MIKTEX_ENABLEWRITE18=t on Windows, and to set shell_escape = t in % texmf.cnf for Tex Live on Unix/Linux/Mac. \usepackage{auto-pst-pdf} \usepackage[authoryear,round]{natbib} \usepackage{hyperref} \textwidth=6.2in \textheight=8.5in %\parskip=.3cm \oddsidemargin=.1in \evensidemargin=.1in \headheight=-.3in \newcommand{\scscst}{\scriptscriptstyle} \newcommand{\scst}{\scriptstyle} \newcommand{\Rfunction}[1]{{\texttt{#1}}} \newcommand{\Robject}[1]{{\texttt{#1}}} \newcommand{\Rpackage}[1]{{\textit{#1}}} \newcommand{\Rmethod}[1]{{\texttt{#1}}} \newcommand{\Rfunarg}[1]{{\texttt{#1}}} \newcommand{\Rclass}[1]{{\textit{#1}}} \textwidth=6.2in \bibliographystyle{plainnat} \begin{document} %\setkeys{Gin}{width=0.55\textwidth} \title{Computations related to the Bioinformatics Applications Note, 2009} \author{VJ Carey stvjc at channing.harvard.edu} \maketitle The main illustrations in the Applications note involve a gene set. All chunks have eval=FALSE; to run this code, please manually reset. <>= library(GGtools) data(hla2set) hla2set @ We need to filter the full HapMap CEU cohort to founders: <>= library(GGdata) data(hmceuB36) hmFou = hmceuB36[, which(hmceuB36$isFounder == TRUE)] @ Now we run the tests: <>= hla2run = gwSnpTests(hla2set~male, hmFou, snpdepth(250)) @ \end{document}