\name{GlmTests-class} \docType{class} \alias{GlmTests-class} \alias{[,GlmTests,ANY,missing,missing-method} \alias{chi.squared,GlmTests,missing-method} \alias{deg.freedom,GlmTests-method} \alias{effect.sign,GlmTests,logical-method} \alias{names,GlmTests-method} \alias{coerce,GlmTests,data.frame-method} \alias{p.value,GlmTests,missing-method} \alias{sample.size,GlmTests-method} \alias{show,GlmTests-method} \alias{summary,GlmTests-method} \alias{GlmTestsScore-class} \alias{[,GlmTestsScore,ANY,missing,missing-method} \alias{pool2,GlmTestsScore,GlmTestsScore,logical-method} \alias{switch.alleles,GlmTestsScore,character-method} \title{Classes "GlmTests" and "GlmTestsScore"} \description{Classes of objects created by \code{\link{snp.lhs.tests}} and \code{\link{snp.rhs.tests}}. The class \code{"GlmTestsScore"} extends the class \code{"GlmTests"} and is invoked by setting the argument \code{score=TRUE} when calling testing functions in order to save the scores and their variances (and covariances) } \section{Objects from the Class}{Objects of class \code{"GlmTests"} have four slots: \describe{ \item{snp.names}{When only single SNPs are tested, a character vector of SNP names. Otherwise a list of such vectors (one for each test)} \item{var.names}{A character vector containing names of variables tested against SNPs} \item{chisq}{A numerical vector of chi-squared test values} \item{df}{An integer vector of degrees of freedom for the tests} \item{N}{A integer vector of the number of samples contributing to each test} } The \code{"GlmTestsScore"} class extends this, adding a slot \code{score} containing a list with elements which are themselves lists with two elements: \describe{ \item{U}{The vector (or matrix) of efficient scores} \item{V}{The upper triangle of the variance-covariance matrix of \code{U}, stored as a vector} } } \section{Methods}{ \describe{ \item{[]}{\code{signature(x = "GlmTests", i = "ANY", j = "missing", drop = "missing")}: Subsetting operator} \item{coerce}{\code{signature(from = "GlmTests", to = "data.frame")}: Simplify object} \item{chi.squared}{\code{signature(x = "GlmTests", df = "missing")}: Extract chi-squared test values} \item{deg.freedom}{\code{signature(x = "GlmTests")}: Extract degrees of freedom for tests} \item{names}{\code{signature(x="GlmTests")}: Extract (or generate) a name for each test} \item{p.value}{\code{signature(x = "GlmTests", df = "missing")}: Extract \emph{p}-values} \item{sample.size}{\code{signature(object = "GlmTests")}: Extract sample sizes for tests} \item{show}{\code{signature(object = "GlmTests")}: Show method} \item{summary}{\code{signature(object = "GlmTests")}: Summary method} \item{[]}{\code{signature(x = "GlmTestsScore", i = "ANY", j = "missing", drop = "missing")}: Subsetting operator} \item{effect.sign}{\code{signature(x = "GlmTestsScore", simplify = "logical")}: Extract signs of associations. If \code{simpify} is \code{TRUE} then a simple vector is returned if all tests are on 1df} \item{pool2}{\code{signature(x = "GlmTestsScore", y = "GlmTestsScore", score = "logical")}: Combine results from two sets of tests} \item{switch.alleles}{\code{signature(x = "GlmTestsScore", snps = "character")}: Emulate, in the score vector and its (co)variances, the effect of switching of the alleles of specified SNPs} } } \author{David Clayton \email{david.clayton@cimr.cam.ac.uk}} \note{Most of the methods for this class are shared with the \code{\linkS4class{SingleSnpTests}} and \code{\linkS4class{SingleSnpTestsScore}} classes } \seealso{\code{\link{snp.lhs.tests}},\code{\link{snp.rhs.tests}}, \code{\linkS4class{SingleSnpTests}}, \code{\linkS4class{SingleSnpTestsScore}} } \examples{ showClass("GlmTests") } \keyword{classes}