\name{tTest} \alias{tTest} \title{Use t Test to Compare Two Groups} \description{ Use a (modified) t test to compare two groups } \usage{ tTest(object, groups, probe2gene = TRUE) } \arguments{ \item{object}{ExpressionSet object} \item{groups}{string indicating the name of the variable of the phenoData containing the group information} \item{probe2gene}{logical; if \code{TRUE} Affymetrix probeset IDs are translated into gene symbols; if \code{FALSE} no such translation is conducted} } \details{ For multiple testing the \code{mt.rawp2adjp} function of package \code{multtest} is used. } \value{ Object of class \code{"tTest"}, a data frame with the following columns \item{gSymbol}{Gene Symbol} \item{p}{TODO} \item{logRatio}{TODO} \item{pBH}{TODO} \item{tStat}{TODO} } \author{Willem Talloen, Tobias Verbeke} \examples{ if (require(ALL)){ data(ALL, package = "ALL") ALL <- addGeneInfo(ALL) ALL$BTtype <- as.factor(substr(ALL$BT,0,1)) tTestRes <- tTest(object = ALL, groups = "BTtype", probe2gene = TRUE) volcanoPlot(tTestRes) } } \seealso{\code{\link[genefilter]{rowttests}}} \keyword{htest}