\name{calcPercentConversion} \alias{calcPercentConversion} %- Also NEED an '\alias' for EACH other topic documented here. \title{ Calculate percent conversion } \description{ Function to calculate percent methylation (wrapper for \code{calcMeth()} function) for each identified conversion control } \usage{ calcPercentConversion(fragments, peaks) } %- maybe also 'usage' for other objects documented here. \arguments{ \item{fragments}{ List of MassArrayFragment objects } \item{peaks}{ List of MassArrayPeak objects comprising spectral data to be used for conversion control calculations } } \details{ This function serves as a wrapper function for \code{calcMeth()}, such that percent methylation is calculated for all conversion controls within the input list of fragments. } \value{ Returns a list of numerical values (from 0 to 1) corresponding to percent methylation for each conversion control, with 0% indicating complete conversion and 1 (100%) indicating a complete failure of bisulphite conversion. Note that each element within the returned list will represent conversion control(s) for a single sample, while each element may contain multiple values with each value corresponding to data obtained from a single conversion control fragment. } \author{ Reid F. Thompson (\email{rthompso@aecom.yu.edu}), John M. Greally (\email{jgreally@aecom.yu.edu}) } \examples{ data(MassArray.example.data) conversion.data <- calcPercentConversion(MassArray.example.data$fragments.T, MassArray.example.data$samples[[1]]$peaks) mean(conversion.data) # NOTE: conversion control data may already be contained within a MassArrayData object; these data can be accessed and visualized by the following (or alternative) commands conversion.data <- unlist(lapply(lapply(MassArray.example.data$samples, slot, "quality.conversion"), median, na.rm=TRUE)) barplot(conversion.data) } \seealso{ See Also \code{\link{calcMeth}}, \code{\link{convControl}} } % Add one or more standard keywords, see file 'KEYWORDS' in the % R documentation directory. \keyword{ attribute } \keyword{ arith }