tilingArray

Analysis of high-density oligonucleotide tiling arrays

The package provides some functionalities that can be useful for the analysis of high-density tiling microarray data (such as Affymetrix genechips) for measuring transcript abundance and architecture. The main functionalities of the package are: The class 'segmentation' for representing partitionings of a linear series of data. The functions 'segment' for fitting piecewise constant models using a dynamic programming algorithm that is both fast and exact, and 'confint' for calculating confidence intervals using the strucchange package. The function 'plotAlongChrom' for generating pretty plots. The function 'normalizeByReference' for probe-sequence dependent response adjustment from a (set of) reference hybridizations.

Author Wolfgang Huber, Joern Toedling, Matt Ritchie
Maintainer W. Huber

To install this package, start R and enter:

    source("http://bioconductor.org/biocLite.R")
    biocLite("tilingArray")

Documentation

Package Downloads

Normalization overview and assessment of signal/noise ratio.
Supplement. Calculation of the cost matrix
Introduction to using the segment function to fit a piecewise constant curve
Segmentation demo
Reference Manual
Package source tilingArray_1.20.0.tar.gz
Windows binary tilingArray_1.20.0.zip
MacOS X 10.4 (Tiger) binary tilingArray_1.20.0.tgz
MacOS X 10.5 (Leopard) binary tilingArray_1.20.0.tgz
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Details

biocViews
Depends
R , methods , Biobase , affy , RColorBrewer , grid , strucchange , vsn , genefilter , geneplotter , pixmap
Imports
Suggests
System Requirements
License The Artistic License, Version 2.0
URL
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Development History Bioconductor Changelog