To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("PWMEnrich")

In most cases, you don't need to download the package archive at all.

PWMEnrich

   

This package is for version 2.12 of Bioconductor; for the stable, up-to-date release version, see PWMEnrich.

PWM enrichment analysis

Bioconductor version: 2.12

Asses the enrichment of already known PWMs (from JASPAR and MotifDb) in DNA sequences. The package implements multiple algorithms, including fixed-threshold (Z-score) and threshold-free (Lognormal normalization and Clover) methods. These can be applied to a single sequence (e.g. enhancer of interest) or a group of sequences (e.g. a set of ChIP-chip/seq peaks). The output is a ranked list of PWMs according to their level of enrichment compared to genomic background. Custom sets of PWMs and genomic background are also supported.

Author: Robert Stojnic, with contributions from Diego Diez

Maintainer: Robert Stojnic <robert.stojnic at gmail.com>

Citation (from within R, enter citation("PWMEnrich")):

Installation

To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("PWMEnrich")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("PWMEnrich")

 

PDF R Script Overview of the 'PWMEnrich' package
PDF   Reference Manual
Text   NEWS

Details

biocViews Bioinformatics, GenomicSequence, SequenceMatching, Software
Version 2.2.0
In Bioconductor since BioC 2.11 (R-2.15) (3.5 years)
License GPL-3
Depends methods, grid, BiocGenerics, Biostrings
Imports seqLogo, gdata, evd
LinkingTo
Suggests MotifDb, BSgenome.Dmelanogaster.UCSC.dm3, PWMEnrich.Dmelanogaster.background, testthat, gtools, parallel
SystemRequirements
Enhances
URL
Depends On Me PWMEnrich.Dmelanogaster.background
Imports Me
Suggests Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source PWMEnrich_2.2.0.tar.gz
Windows Binary PWMEnrich_2.2.0.zip
Mac OS X 10.6 (Snow Leopard) PWMEnrich_2.2.0.tgz
Subversion source (username/password: readonly)
Git source https://github.com/Bioconductor-mirror/PWMEnrich/tree/release-2.12
Package Short Url http://bioconductor.org/packages/PWMEnrich/
Package Downloads Report Download Stats

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