\name{resamplingPvalues} \Rdversion{1.4} \alias{resamplingPvalues} \title{ Resampling of microarray expression values and test for differential expression. } \description{ The function uses a 50\% jackknife resampling to calculate a pseudo-replicate of the expression matrix. The resampled expression values are used thereupon to calculate p-values for the differential expression between the given groups. Only two-group comparisons are allowed for the perfomed t-test. } \usage{ resamplingPvalues(exprMat, groups, alternative = c("two.sided", "less", "greater"), resampleMat=FALSE) } \arguments{ \item{exprMat}{Matrix with microarray expression values.} \item{groups}{Factors for two groups that are tested for differential expression.} \item{alternative}{Testing alternatives for the t-test: "two.sided", "less" or "greater".} \item{resampleMat}{Boolean value, whether to retrieve the matrix of jacknife resamples or not.} } \value{ A result list is returned, consisting of: \item{p.values}{VNumerical vector of p-values.} \item{resampleMat}{Matrix of resampled expression values.} } \author{ Daniela Beisser } \examples{ library(ALL) data(ALL) mat <- exprs(ALL) groups <- factor(c(rep("A", 64), rep("B", 64))) results <- resamplingPvalues(mat, groups, alternative="greater") }