To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("PWMEnrich")

In most cases, you don't need to download the package archive at all.

PWMEnrich

   

This package is for version 2.11 of Bioconductor; for the stable, up-to-date release version, see PWMEnrich.

PWM enrichment analysis

Bioconductor version: 2.11

Asses the enrichment of already known PWMs (e.g. from JASPAR) in DNA sequences. Motif hits in a sequence or DNA region are considered together and P-values derived for their joint pattern. The package implements multiple algorithms, including fixed-threshold (Z-score) and threshold-free (Lognormal normalization and Clover) methods. The main goal is to identify a set of transcription factors that most likely bind to a single sequence, group of sequences, or show significantly different binding affinity between two sets of sequences.

Author: Robert Stojnic

Maintainer: Robert Stojnic <robert.stojnic at gmail.com>

Citation (from within R, enter citation("PWMEnrich")):

Installation

To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("PWMEnrich")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("PWMEnrich")

 

PDF R Script Overview of the 'PWMEnrich' package
PDF   Reference Manual
Text   NEWS

Details

biocViews Bioinformatics, SequenceMatching, Software
Version 1.2.0
In Bioconductor since BioC 2.11 (R-2.15) (3.5 years)
License GPL-3
Depends methods, Biostrings, grid
Imports seqLogo, gdata, evd
LinkingTo
Suggests BSgenome.Dmelanogaster.UCSC.dm3, PWMEnrich.Dmelanogaster.background, testthat, gtools, parallel
SystemRequirements
Enhances
URL
Depends On Me PWMEnrich.Dmelanogaster.background
Imports Me
Suggests Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source PWMEnrich_1.2.0.tar.gz
Windows Binary PWMEnrich_1.2.0.zip
Mac OS X 10.6 (Snow Leopard)
Subversion source (username/password: readonly)
Git source https://github.com/Bioconductor-mirror/PWMEnrich/tree/release-2.11
Package Short Url http://bioconductor.org/packages/PWMEnrich/
Package Downloads Report Download Stats

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