\name{makeMyD} \alias{makeMyD} \title{A function to convert the X expression matrix into the D correlation matrix} \description{ A function to convert the X expression matrix into the D correlation matrix; uses either Pearson's correlation coefficient or biweight midcorrelation } \usage{ makeMyD(X, conditions, useBWMC = FALSE, gpsep = "~") } \arguments{ \item{X}{ An m-by-n expression matrix, where rows are genes and columns are chips (subjects); include all chips in X, indicate condition in the conditions array %% ~~Describe \code{X} here~~ } \item{conditions}{ The conditions array } \item{useBWMC}{ Should biweight midcorrelation be used instead of Pearson's correlation coefficient? } \item{gpsep}{ A separator that indicates a gene-pair, such as P53~MAPK1. The separator should not appear in any of the gene names } } \value{ A p-by-K matrix of observed correlations for all p gene-pairs, where p is choose(m,2), m is the 1st dimension of X and K is the number of conditions specified by the conditions array } \references{ Dawson JA and Kendziorski C. An empirical Bayesian approach for identifying differential co-expression in high-throughput experiments. (2011) Biometrics. E-publication before print: http://onlinelibrary.wiley.com/doi/10.1111/j.1541-0420.2011.01688.x/abstract } \author{ John A. Dawson } \examples{ data(fiftyGenes) tinyCond <- c(rep(1,100),rep(2,25)) tinyPat <- ebPatterns(c("1,1","1,2")) D <- makeMyD(fiftyGenes, tinyCond, useBWMC=TRUE) } \keyword{ models }