LPEadj

A correction of the local pooled error (LPE) method to replace the asymptotic variance adjustment with an unbiased adjustment based on sample size.

Bioconductor version: Development (2.8)

Two options are added to the LPE algorithm. The original LPE method sets all variances below the max variance in the ordered distribution of variances to the maximum variance. in LPEadj this option is turned off by default. The second option is to use a variance adjustment based on sample size rather than pi/2. By default the LPEadj uses the sample size based variance adjustment.

Author: Carl Murie, Robert Nadon

Maintainer: Carl Murie

To install this package, start R and enter:

source("http:///biocLite.R")
biocLite("LPEadj")    

Documentation

PDF

R Script

LPEadj test for microarray data with small number of replicates

Reference Manual

Details

biocViews	Microarray, Bioinformatics, Differential Expression, Proteomics
Depends	LPE
Imports	LPE, stats
Suggests
System Requirements
License	LGPL
URL
Depends On Me
Imports Me
Suggests Me
Version	1.11.0

Package Downloads

Package Source	LPEadj_1.11.0.tar.gz
Windows Binary	LPEadj_1.11.0.zip (32- & 64-bit)
MacOS 10.5 (Leopard) binary	LPEadj_1.11.0.tgz
Package Downloads Report	Download Stats