Changes in version 0.99.0 o BERT has been released. o BERT provides an hierarchical approach to batch effect adjustment with tolerance to missing values. BERT has been found to outperform similar algorithmms, e.g. HarmonizR with regard to execution time, preservation of numerical values in the input data and flexibility wrt. covariables and references. o The authors can be contacted via the BioConductor forum, GitHub issues and via email.