scMerge
This package is for version 3.9 of Bioconductor; for the stable, up-to-date release version, see scMerge.
scMerge: Merging multiple batches of scRNA-seq data
Bioconductor version: 3.9
Like all gene expression data, single-cell RNA-seq (scRNA-Seq) data suffers from batch effects and other unwanted variations that makes accurate biological interpretations difficult. The scMerge method leverages factor analysis, stably expressed genes (SEGs) and (pseudo-) replicates to remove unwanted variations and merge multiple scRNA-Seq data. This package contains all the necessary functions in the scMerge pipeline, including the identification of SEGs, replication-identification methods, and merging of scRNA-Seq data.
Author: Kevin Wang [aut, cre], Yingxin Lin [aut], Sydney Bioinformatics and Biometrics Group [fnd]
Maintainer: Kevin Wang <kevin.wang at sydney.edu.au>
citation("scMerge")):
Installation
To install this package, start R (version "3.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("scMerge")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("scMerge")| scMerge | HTML | R Script |
| Reference Manual | ||
| NEWS | Text |
Details
| biocViews | BatchEffect, GeneExpression, Normalization, RNASeq, Sequencing, SingleCell, Software, Transcriptomics |
| Version | 1.0.0 |
| In Bioconductor since | BioC 3.9 (R-3.6) (5 years) |
| License | GPL-3 |
| Depends | R (>= 3.6.0) |
| Imports | BiocParallel, cluster, distr, doSNOW, foreach, igraph, irlba, iterators, matrixStats, M3Drop(>= 1.9.4), parallel, pdist, proxy, Rcpp (>= 0.12.18), RcppEigen (>= 0.3.3.4.0), ruv, rsvd, S4Vectors, SingleCellExperiment, SummarizedExperiment |
| System Requirements | |
| URL | https://github.com/SydneyBioX/scMerge |
| Bug Reports | https://github.com/SydneyBioX/scMerge/issues |
See More
| Suggests | BiocStyle, covr, knitr, Matrix, rmarkdown, scales, scater, testthat |
| Linking To | Rcpp (>= 0.12.18), RcppEigen, testthat |
| Enhances | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | scMerge_1.0.0.tar.gz |
| Windows Binary | scMerge_1.0.0.zip (32- & 64-bit) |
| Mac OS X 10.11 (El Capitan) | scMerge_1.0.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/scMerge |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/scMerge |
| Bioc Package Browser | https://code.bioconductor.org/browse/scMerge/ |
| Package Short Url | https://bioconductor.org/packages/scMerge/ |
| Package Downloads Report | Download Stats |
| Old Source Packages for BioC 3.9 | Source Archive |