Changes in version 1.4.0: NEW FEATURES o interest() and interest.sequential() functions now support "IntSpan" method, allows counting intron- spanning reads. o psi() function is added. It calculates Psi values. o annotateU12() fucntion supports DNAStringSet objects as its refGenome input. o Improved vignette document. SIGNIFICANT USER-VISIBLE CHANGES o eBayesInterest() removed. BUG FIXES o interest.sequential() and interest() corrections to their object output option. o annotateU12() modified to work correctly with the new changes in Biostrings package.