IHW
This package is for version 3.14 of Bioconductor; for the stable, up-to-date release version, see IHW.
Independent Hypothesis Weighting
Bioconductor version: 3.14
Independent hypothesis weighting (IHW) is a multiple testing procedure that increases power compared to the method of Benjamini and Hochberg by assigning data-driven weights to each hypothesis. The input to IHW is a two-column table of p-values and covariates. The covariate can be any continuous-valued or categorical variable that is thought to be informative on the statistical properties of each hypothesis test, while it is independent of the p-value under the null hypothesis.
Author: Nikos Ignatiadis [aut, cre], Wolfgang Huber [aut]
Maintainer: Nikos Ignatiadis <nikos.ignatiadis01 at gmail.com>
citation("IHW")):
Installation
To install this package, start R (version "4.1") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("IHW")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("IHW")| Introduction to IHW | HTML | R Script |
| Reference Manual |
Details
| biocViews | ImmunoOncology, MultipleComparison, RNASeq, Software |
| Version | 1.22.0 |
| In Bioconductor since | BioC 3.3 (R-3.3) (8 years) |
| License | Artistic-2.0 |
| Depends | R (>= 3.3.0) |
| Imports | methods, slam, lpsymphony, fdrtool, BiocGenerics |
| System Requirements | |
| URL |
See More
| Suggests | ggplot2, dplyr, gridExtra, scales, DESeq2, airway, testthat, Matrix, BiocStyle, knitr, rmarkdown, devtools |
| Linking To | |
| Enhances | |
| Depends On Me | IHWpaper |
| Imports Me | ideal |
| Suggests Me | BloodCancerMultiOmics2017, DEWSeq, metagenomeSeq, SummarizedBenchmark |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | IHW_1.22.0.tar.gz |
| Windows Binary | IHW_1.22.0.zip |
| macOS 10.13 (High Sierra) | IHW_1.22.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/IHW |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/IHW |
| Bioc Package Browser | https://code.bioconductor.org/browse/IHW/ |
| Package Short Url | https://bioconductor.org/packages/IHW/ |
| Package Downloads Report | Download Stats |
| Old Source Packages for BioC 3.14 | Source Archive |