Changes in version 1.2.4 (2020-08-14) - Supported defining gene set database from score matrix by setting higher, lower, as well as padj cutoffs for gCMAP and Fisher GESS methods Changes in version 1.2.2 (2020-07-11) - Supported converting gmt file to HDF5 file (01 matrix) as gene set reference database for gCMAP and Fisher GESS methods Changes in version 1.0.6 (2020-04-19) - Supported searching refdb parallelly by using multiple cores on a single machine Changes in version 1.0.5 (2020-04-10) - Fix bug: fixed null issue and throw warning messages when up or down gene sets share zero identifiers with refdb for gess_lincs method. Changes in version 1.0.4 (2020-04-02) - Added instructions for GESS batch queries in vignette - Added runWF function to run entire GESS/FEA workflow Changes in version 1.0.3 (2020-02-07) - Supported converting feaResult object to enrichResult object in the clusterProfiler package so that the plotting functionalities in the latter package such as dotplots and gene-concept networks could be applied to the FEA enrichment results - Supported searching against subset of refdb (subsetted specific columns (treatments) in the refdb (e.g. lincs)) for GESS methods - Updated comp_fea_res function to reduce number of characters in description - Added functions to draw different types of query GESs from refdb - Added deprof2subexpr function to get a subset of gene expression values from a differential expression profile Changes in version 1.0.2 (2020-01-21) - Fix bug: the enrichment results from DSEA methods and some of TSEA methods were added an aditional 'ont' column where the GO itmes were subsetted to the selected ontology Changes in version 1.0.1 (2019-11-10) - Support windows by not depending gCMAP package - Deal with HDF5 files with functions in HDF5Array package Changes in version 1.0.0 (2019-10-23) - Initial version Changes in version 0.99.20 (2019-10-22) - Submitted to Bioconductor - Major changes - used HDF5 file to read and write the matrix in batches - data stored in ExperimentHub