escalation 0.1.6
- Implement efficient simulation comparison method of Sweeting et al. in simulate_compare()
- Implement BOIN12 design
- Add MTD / OBD selectors for TPI, mTPI, mTPI2 and BOIN12 for final dose choice at end of a trial
escalation 0.1.5
- Add mTPI2 dose-finding method
- Fixed some bugs
escalation 0.1.4
- Added Neuenschwander, Branson & Sponer’s method for phase I.
- Added Ji et al.’s TPI & mTI methods for phase I.
- Added Thall & Cook’s EffTox method for phase I/II.
- Added Wages & Tait’s method for phase I/II.
escalation 0.1.3
- Mainly small changes to comply with dplyr v1.0.
- simulations and crystallised_dose_paths given summary method
- NOTE squash
escalation 0.1.2
- Methods for simulation and calculating dose-paths added.
- A bit more on the general selector interface.
- Everything new has tests, and more tests on old stuff.
escalation 0.1.1
- Initial release.
- dfcrm, BOIN, 3+3 models supported.
- several objects included to facilitate stopping at different events.
- class for a fixed escalation plan included, as sometimes used with CRM.