Changes in version 0.99.5 Changes regarding the second round of comments during the Bioconductor submission review: - Minor changes to SCAE-show method - Extended and moved installation-checks for packages used in optional functionalities to the SCAE-constructor - Extended checks for the rowData setter - Extended unit tests to increase coverage Changes in version 0.99.4 Changes regarding the first round of comments during the Bioconductor submission review: Removed multiple dependencies, now listed as suggested - computation of the logcounts assay now optional - computation of a knee plot and according inflection/knee points now optional - computation of new gene-symbols now optional - minor changes in tests (needs to be extended to test for new optional code); also extension of the tests to check new code - major changes in package structure and organisation - reworked vignette to include optional features Changes in version 0.99.3 - retriggering bioc build during package submission. Changes in version 0.99.2 - minor changes in the vignette to reduce build-time. Content is the same. Changes in version 0.99.1 - minor changes made regarding the Bioconductor submission review of scaeData which also affected this package. Changes in version 0.99.0 - The package is defining a S4 class that is extending the SingleCellExperiment class. The multi-layer data structure integrates data for immune genes at allele and functional level. - Workflow: To be able to generate a SingleCellAlleleExperiment object the data has to be generated by the connected workflow single-cell ImmunoGenomic Diversity (scIGD) which performs allele typing and quantification of genes and typed alleles. Use the read_allele_counts() function to read in the data and generate an SCAE object. This function also offers parameters to perform filtering on the data, as well as visualize the filtering step in a so called knee plot.